4L液质联用乙腈

检测项目Test Items

指标要求Specifications

含量 Assay CH₃CN(GC)

≥99.99

密度Density(20℃)

0.782～0.785

与水混合试验Solubility with H₂O

合格Pass test

蒸发残渣Residue on evaporation

≤0.0001

水分Water

≤0.01

酸度Acidity(as H⁺)

≤0.0002

碱度Alkalinity(as OH^-)

≤0.0001

吸光度Absorbance at 190 nm

≤0.60

吸光度Absorbance at 195 nm

≤0.07

吸光度Absorbance at 200 nm

≤0.01

吸光度Absorbance at 210 nm

≤0.01

吸光度Absorbance at 220 nm

≤0.008

吸光度Absorbance at 230 nm

≤0.004

吸光度Absorbance at 240 nm

≤0.004

吸光度Absorbance at 254 nm

≤0.004

梯度洗脱试验：254nm所有峰的吸光度Gradient Elution Test

≤0.5

梯度洗脱试验：210nm所有峰的吸光度Gradient Elution Test

≤2

荧光杂质

Fluorescence impurity at 254 nm

≤0.5

荧光杂质

Fluorescence impurity at 365 nm

≤0.5

LC-MS(正离子模式)以利血平计LC-MS(ESI⁺)as reserpine

≤50

LC-MS(负离子模式)以4-硝基苯酚计LC-MS(ESI^-) as 4-nitrophenol

≤50

钾、银、钡、镉、钴、铬、铜、锰、镍、铅、锡(K、Ag、Ba、Cd、Co、Cr、Cu、Mn、Ni、Pb、Sn)

≤5

铝、钙、镁、铁Al、Ca、Mg、Fe

≤10

钠Na

≤50